Influence of tumor characteristics (Lesion type, stage, grade) on postoperative outcomes following holmium laser resection –  A cross-sectional observational study.

Thota  Siddhartha; Suvit  Jumde

doi:10.51168/sjhrafrica.v6i6.1887

Authors

Thota Siddhartha Assistant Professor, Department of Urology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India,
Suvit Jumde Assistant Professor, Department of Urology, Himalayan Institute of Medical Sciences, Dehradun, India

DOI:

https://doi.org/10.51168/sjhrafrica.v6i6.1887

Keywords:

Tumor, Bladder, TURBT, Holmium Laser, Outcomes, Transurethral resection of the bladder tumor

Abstract

Background

Transurethral resection of the bladder tumor (TURBT) is the usual treatment for these tumors, which is followed by further intravesical chemotherapy or immunotherapy. But problems, including bleeding, obturator nerve reflex (ONR), and bladder perforation, are linked to TURBT.

Objectives- The study primarily evaluated the impact of tumor attributes, including lesion kind, stage, and grade, on the results of surgery after Holmium laser resection.

Materials and methods

It was a cross-sectional, observational study. The study was carried out in the Department of Urology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India. The study was conducted for one and a half years, that is, from December 2021 to Jun 2023. In all, 24 patients were enrolled.

Results

Seven patients (29.2%) had numerous lesions, compared to the majority of 17 patients (70.8%) who had single lesions. Ten (41.7%) patients had high-grade cancers, whereas 14 (58.3%) patients had low-grade tumors. With a p-value of 0.017, patients with many lesions needed many more analgesic vials after surgery. Catheterization time, hospital stay, analgesic use, and operation time did not significantly change between the T1 and Ta stages.

Conclusion

This study demonstrates that among the various tumor characteristics evaluated, only the presence of multiple lesions significantly influenced postoperative outcomes, specifically resulting in increased analgesic requirements.

Recommendations

Larger, multicenter studies are recommended to validate these findings and assess long-term outcomes.

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