Impact of Body Mass Index on renal outcomes following Percutaneous nephrolithotomy: A cross-sectional study.
DOI:
https://doi.org/10.51168/sjhrafrica.v6i6.1898Keywords:
Nephrolithiasis, PCNL, Body mass index, renal function, percutaneous nephrolithotomyAbstract
Background
Observation, medication, or procedures that are invasive, such as percutaneous nephrolithotomy (PCNL), ureteroscopy, or even laparoscopic surgeries for instances that are severe, are among the management protocols for kidney stones. Body mass index (BMI) has a variable effect on PCNL outcome, despite obesity being linked to higher rates of perioperative complications and all-cause mortality.
Objectives- The study was conducted to evaluate the effect of BMI on renal outcomes following PCNL.
Materials and methods
It was a cross-sectional study. The study was carried out at the Department of Urology, Mahatma Gandhi Medical College and Research Institute, Puducherry, India. The study was conducted for one and a half years, that is, from October 2022 to April 2024. In all, 40 patients were enrolled.
Results
In comparison to the normal BMI group, which had a mean serum creatinine level of 1.13 ± 0.40 mg/dL, the increased BMI group had a slightly higher mean level of 1.22 ± 0.49 mg/dL. Thirty-five (97.2%) patients in the normal BMI group exhibited normal echogenicity, whereas three (75%) of the participants in the increased BMI group did the same.
Conclusion
Patients with elevated BMI had slightly higher serum creatinine levels, higher resistive index values, and a lower incidence of normal renal echogenicity, suggesting early morphological changes, even though overall renal function and vascular resistance stayed within normal limits in both groups.
Recommendation
Patients with elevated BMI undergoing percutaneous nephrolithotomy (PCNL) should be closely monitored for early renal morphological changes and subtle functional alterations to prevent long-term renal complications.
References
Wang W, Fan J, Huang G, Li J, Zhu X, Tian Y, Su L. Prevalence of kidney stones in mainland China: a systematic review. Scientific reports. 2017 Jan 31;7(1):41630. https://doi.org/10.1038/srep41630 PMid:28139722 PMCid:PMC5282506
Romero V, Akpinar H, Assimos DG. Kidney stones: a global picture of prevalence, incidence, and associated risk factors. Reviews in Urology. 2010;12(2-3):e86.
Leveridge M, D'Arcy FT, O'Kane D, Ischia JJ, Webb DR, Bolton DM, Lawrentschuk N. Renal colic: current protocols for emergency presentations. European Journal of Emergency Medicine. 2016 Feb 1;23(1):2-7. https://doi.org/10.1097/MEJ.0000000000000324 PMid:26367338
Zisman AL. Effectiveness of treatment modalities on kidney stone recurrence. Clinical Journal of the American Society of Nephrology. 2017 Oct 1;12(10):1699-708. https://doi.org/10.2215/CJN.11201016 PMid:28830863 PMCid:PMC5628726
Taylor EN, Stampfer MJ, Curhan GC. Obesity, weight gain, and the risk of kidney stones. Jama. 2005 Jan 26;293(4):455-62. https://doi.org/10.1001/jama.293.4.455 PMid:15671430
El-Nahas AR, El-Assmy AM, Mansour O, Sheir KZ. A prospective multivariate analysis of factors predicting stone disintegration by extracorporeal shock wave lithotripsy: the value of high-resolution noncontrast computed tomography. European urology. 2007 Jun 1;51(6):1688-94. https://doi.org/10.1016/j.eururo.2006.11.048 PMid:17161522
Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M, Knoll T. EAU guidelines on interventional treatment for urolithiasis. European urology. 2016 Mar 1;69(3):475-82. https://doi.org/10.1016/j.eururo.2015.07.041 PMid:26344917
Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: a systematic review and meta-analysis. Jama. 2013 Jan 2;309(1):71-82.
https://doi.org/10.1001/jama.2012.113905 PMid:23280227 PMCid:PMC4855514
Fuller A, Razvi H, Denstedt JD, Nott L, Pearle M, Cauda F, Bolton D, Celia A, De La Rosette J, CROES PCNL Study Group. The CROES percutaneous nephrolithotomy global study: the influence of body mass index on outcome. The Journal of Urology. 2012 Jul 1;188(1):138-44. https://doi.org/10.1016/j.juro.2012.03.013 PMid:22591971
Zhou X, Sun X, Chen X, Gong X, Yang Y, Chen C, Yao Q. Effect of obesity on outcomes of percutaneous nephrolithotomy in renal stone management: a systematic review and meta-analysis. Urologia Internationalis. 2017 Feb 3;98(4):382-90. https://doi.org/10.1159/000455162 PMid:28152527
Zhang T, He Y, Wang Y, Zhu Q, Yang J, Zhao X, Sun Y. The role of three-dimensional power Doppler ultrasound parameters measured on hCG day in the prediction of pregnancy during in vitro fertilization treatment. European Journal of Obstetrics & Gynecology and Reproductive Biology. 2016 Aug 1;203:66-71. https://doi.org/10.1016/j.ejogrb.2016.05.016 PMid:27254812
Fuller A, Razvi H, Denstedt JD, Nott L, Pearle M, Cauda F, Bolton D, Celia A, De La Rosette J, CROES PCNL Study Group. The CROES percutaneous nephrolithotomy global study: the influence of body mass index on outcome. The Journal of Urology. 2012 Jul 1;188(1):138-44. https://doi.org/10.1016/j.juro.2012.03.013 PMid:22591971
Sancak EB, Reşorlu M, Akbas A, Gulpinar MT, Arslan M, Resorlu B. Do Hypertension, diabetes mellitus, and obesity increase the risk of severity of nephrolithiasis?. Pakistan journal of medical sciences. 2015 May;31(3):566.
https://doi.org/10.12669/pjms.313.7086 PMid:26150845 PMCid:PMC4485272
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