PRP injection after manipulation under anesthesia in diabetic frozen shoulder: a prospective observational study.
DOI:
https://doi.org/10.51168/sjhrafrica.v7i3.2530Keywords:
Frozen shoulder, Platelet-rich plasma, PRP, Diabetes mellitus, Adhesive capsulitis, Manipulation under anesthesia,, Intra-articular injectionAbstract
Background:
Adhesive capsulitis is a debilitating condition with increased severity in diabetic patients. Platelet-rich plasma (PRP) offers a potential alternative to corticosteroids without metabolic side effects.
Methods:
This prospective observational study included 31 diabetic patients with frozen shoulder treated with manipulation under anesthesia followed by intra-articular PRP injection. Pain and function were assessed using the Visual Analogue Scale (VAS) and Constant Shoulder Score (CSS) at baseline, 2 weeks, and 4 weeks.
Results:
The mean age was 57.58 ± 8.67 years, with female predominance (64.5%). Mean VAS decreased from 8.58 ± 0.76 to 2.80 ± 1.04 at 4 weeks. Mean CSS improved from 23.81 ± 8.12 to 59.39 ± 8.39. No major complications were observed.
Conclusion:
PRP injection following MUA is a safe and effective treatment for diabetic frozen shoulder, providing significant pain relief and functional improvement.
Recommendation:
Further randomized controlled trials with a larger sample size and longer follow-up are recommended.
References
Bunker TD. Shoulder Elbow. 2009;1(1):4-9.https://doi.org/10.1111/j.1758-5740.2009.00007.x
Bridgman JF. Ann Rheum Dis. 1972;31(1):69-72.https://doi.org/10.1136/ard.31.1.69
Habib GS, et al. Clin Rheumatol. 2010;29(5):501-505.https://doi.org/10.1007/s10067-009-1357-y
Dhurat R, Sukesh M. J Cutan Aesthet Surg. 2014;7(4):189-197.https://doi.org/10.4103/0974-2077.150734
Andia I, Maffulli N. Nat Rev Rheumatol. 2013;9(12):721-730.https://doi.org/10.1038/nrrheum.2013.141
Scarpone M, et al. Pain Med. 2013;14(1):122-129.
Halim A, et al. Orthop Rev (Pavia). 2020;12(4):9103.
Pandey V, et al. J Shoulder Elbow Surg. 2016;25(10):1511-1518.https://doi.org/10.1016/S1058-2746(15)00635-7
Ouyang Y, et al. BMC Musculoskelet Disord. 2024;25:667.https://doi.org/10.1186/s12891-024-07592-x
Lum ZC, et al. J Shoulder Elbow Surg. 2023;32(10 Suppl):e515-e523.
Paxinos O, et al. Arch Orthop Trauma Surg. 2007;127(6):405-410.
Mueller M, et al. Int J Surg. 2021;96:106167.https://doi.org/10.17762/turcomat.v12i1S.1568
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Dr. Aman Goel, Dr. Kavita Gupta
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
