An observational cohort study to determine the clinical profile, angiographic profile, and outcomes of patients with left bundle branch block without previous heart disease from a tertiary care centre in north India.

Biswojit  Maharatha; Manish  Kumar; Priyanka  Kumari

doi:10.51168/sjhrafrica.v6i9.1999

Authors

Biswojit Maharatha Assistant Professor, Department of Cardiology, LPS Institute of Cardiology, GSVM Medical College, India
Manish Kumar Assistant Professor, Department of Cardiology, LPS Institute of Cardiology, GSVM Medical College Kanpur, India
Priyanka Kumari Assistant Professor, Department of Pediatrics, MRMCH Palamu, India

DOI:

https://doi.org/10.51168/sjhrafrica.v6i9.1999

Keywords:

LBBB, coronary artery disease, echocardiography, hypertension, ejection fraction, cholesterol, angiography

Abstract

Background:

Left Bundle Branch Block (LBBB) is a significant electrocardiographic finding often associated with structural heart disease and adverse cardiovascular outcomes. It alters ventricular activation and may mask or mimic myocardial infarction on ECG. Early identification and evaluation are essential for prognosis and management. This study aimed to analyze clinical, echocardiographic, and angiographic profiles of patients with LBBB.

Methods:

This was a prospective, observational cohort study conducted over two years at a tertiary care cardiology center. One hundred patients with complete LBBB and stable hemodynamics were enrolled via random sampling. Data were collected through structured proformas, clinical exams, 2D echocardiography, and coronary angiography. Statistical analysis was done using SPSS, with significance set at p < 0.05.

Results:

Among 100 participants (mean age 58 ± 8.5 years; 67% male), chest pain (73%) and hypertension (62%) were the most common findings. Mean cholesterol and triglyceride levels were 203.6 mg/dL and 109.5 mg/dL, respectively, with an average BMI of 25.3 kg/m². Significant associations were found for chest pain, hypertension, and angiographic disease patterns (p < 0.001). Cholesterol showed a strong positive correlation with triglycerides (r = 0.96, p < 0.001), indicating elevated cardiovascular risk in patients with LBBB.

Conclusion:

LBBB is strongly associated with cardiovascular risk factors and may indicate underlying coronary artery disease and systolic dysfunction.

Recommendation:

Regular cardiovascular screening and timely coronary evaluation are recommended for patients with LBBB to detect and manage underlying ischemic heart disease early.

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