SERUM VITAMIN D3 LEVEL IN MIGRAINE PATIENTS- A HOSPITAL BASED CASE-CONTROL STUDY.

Sujata  Panda; Sasmita  Sahu; Sanghamitra  Bhoi; Jyotsna  Kiro; Mamata  Pandey; Bimal Krushna  Panda

doi:10.51168/sjhrafrica.v4i9.660

Authors

Sujata Panda Department of ENT, VIMSAR, Burla, Odisha, India
Sasmita Sahu Department of Ophthalmology, VIMSAR, Burla, Odisha, India
Sanghamitra Bhoi Department of Biochemistry, VIMSAR, Burla, Odisha, India
Jyotsna Kiro Department of Biochemistry, VIMSAR, Burla, Odisha, India4 Mamata Pandey, Research Scientist –II, MRU, VIMSAR, Burla, Odisha, India.
Mamata Pandey MRU, VIMSAR, Burla, Odisha, India.
Bimal Krushna Panda Department of Anesthesiology (Nodal Officer, MRU, VIMSAR, Burla, Odisha, India

DOI:

https://doi.org/10.51168/sjhrafrica.v4i9.660

Keywords:

Migraine, Serum vitamin D3

Abstract

Introduction: The most prevalent type of headache is migraine and it typically presents with a unilateral, pulsatile severe headache lasting from 4 to 72 hours accompanied by nausea, photophobia, and transient neurological symptoms. Also, in recent years Vit D₃ deficiency has emerged as a global public health problem amounting to about 30-80% of children and adults having Vit. D₃ deficiency. The study was to be taken for the role of vitamin D₃ in the severity of migraine patients.

Materials and Methods: This case-control study was conducted in the Department of ENT and Biochemistry, VIMSAR Burla from January 2023 to June 2023. Age groups of 10 - 60 years of either sex (sample size 65 each) were examined clinically and the severity of migraine was evaluated by MIDAS Score and Biochemical estimation of serum vitamin D₃ level was done by CLIA analyzer (Electra FA). Statistical analysis was performed with SPSS software version 21.0 (SPSS IBM corporation, Armonk. New York). The p-value < 0.05 was taken as statistically significant.

Results: A total of 65 subjects each from case (clinically diagnosed cases of migraine patients) and control group were evaluated. In the present study, 21 males and 44 females were from the case and 22 males and 43 females were included in control groups. The mean age of males and females were (43.23± 2.3) and (32.58 ± 2.4) in case (42.23± 2.5) and (36.58 ± 2.6) were in control groups. Serum vitamin D₃ level was lower in case groups (18.01 ng/mL) and in control, it was (34.09 ng/mL). The association of serum vitamin D₃ concentration with case and control was highly significant (p<0.05).

Conclusion: There was a significant deficiency of Vitamin D₃ in migraine patients as compared to control where serum vitamin D3 levels were normal.

Author Biographies

Sujata Panda, Department of ENT, VIMSAR, Burla, Odisha, India

Assistant Professor, Department of ENT, VIMSAR, Burla, Odisha, India

Sasmita Sahu, Department of Ophthalmology, VIMSAR, Burla, Odisha, India

Assistant Professors, Department of Ophthalmology, VIMSAR, Burla, Odisha, India

Sanghamitra Bhoi, Department of Biochemistry, VIMSAR, Burla, Odisha, India

Assistant Professor, Department of Biochemistry, VIMSAR, Burla, Odisha, India

Jyotsna Kiro, Department of Biochemistry, VIMSAR, Burla, Odisha, India4 Mamata Pandey, Research Scientist –II, MRU, VIMSAR, Burla, Odisha, India.

Assistant Professor, Department of Biochemistry, VIMSAR, Burla^, Odisha, India⁴ Mamata Pandey, Research Scientist –II, MRU, VIMSAR, Burla, Odisha, India.