Metabolic Syndrome in Patients with Lichen Planus: A Case-Control Study.

Swati  Sarangi; Itismita  Sahu; Duryodhan  Sahoo

doi:10.51168/sjhrafrica.v7i3.2574

Authors

Swati Sarangi Assistant Professor, Department of Dermatology, Venereology & Leprosy, Dharanidhar Medical College and Hospital, Keonjhar, Odisha, India
Itismita Sahu Assistant Professor, Department of Dermatology, Venereology& Leprosy, Pabitra Mohan Pradhan Medical College & Hospital, Talcher, Angul, Odisha, India
Duryodhan Sahoo Assistant Professor, Department of Biochemistry, Dharanidhar Medical College and Hospital, Keonjhar, Odisha, India

DOI:

https://doi.org/10.51168/sjhrafrica.v7i3.2574

Keywords:

Lichen planus, metabolic disorders, obesity, hypertension, dyslipidemia

Abstract

Background:

Lichen planus is a chronic inflammatory disorder that has been increasingly associated with metabolic abnormalities.

Aim:

To assess the prevalence of metabolic syndrome in patients with lichen planus and compare it with that of healthy controls.

Methods:

This retrospective case-control study was conducted over one year and included 80 participants (40 cases and 40 age- and sex-matched controls). Clinical and biochemical parameters, including body mass index, blood pressure, fasting blood glucose, and lipid profile, were evaluated. Metabolic syndrome was defined using standard criteria. Statistical analysis was performed using SPSS software, and p < 0.05 was considered significant.

Results:

The mean age of participants was 42.6 ± 10.2 years in cases and 41.8 ± 9.7 years in controls. Metabolic syndrome was observed in 48% of lichen planus patients compared to 20% of controls (p = 0.006). Obesity, hypertension, diabetes, and dyslipidemia were significantly higher in cases.

Conclusion:

Lichen planus is significantly associated with metabolic syndrome.

Recommendation:

Routine screening for metabolic syndrome in patients with lichen planus is recommended to reduce long-term cardiovascular risk.

Author Biography

Swati Sarangi, Assistant Professor, Department of Dermatology, Venereology & Leprosy, Dharanidhar Medical College and Hospital, Keonjhar, Odisha, India

is an Assistant Professor in Dermatology with research interests in inflammatory skin disorders and metabolic diseases.

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