A Comparative Analysis of Pap Smear and Colposcopic Findings in Individuals Presenting with Vaginal Discharge at a Tertiary Care Outpatient Department
Keywords:
Cervical cancer screening, Pap smear, colposcopy, precancerous lesions, cervical intraepithelial neoplasiaAbstract
Background: Cervical cancer is a predominant cause of cancer-related mortality in women globally; nevertheless, it is predominantly preventable via early detection and intervention. Screening techniques like as the Pap smear and colposcopy are essential for detecting precancerous lesions, facilitating prompt intervention and alleviating disease burden.
Methods: This cross-sectional study was conducted in the Obstetrics and Gynecology Department at Sri Krishna Medical College and Hospital, Muzaffarpur, Bihar, over one year. A total of 250 women aged 35–55 years underwent Pap smear, colposcopy, and biopsy for cervical lesion assessment.
Results: Among the participants, 34.0% had high-grade squamous intraepithelial lesions (HSIL), 22.4% had low-grade squamous intraepithelial lesions (LSIL), and 21.2% showed inflammatory changes on Pap smear. Colposcopy revealed CIN I in 48.0% of cases, CIN II–III in 36.4%, and CIN III in 15.6%. Histopathological confirmation showed 83.2% had precancerous lesions, with 7.2% diagnosed with squamous cell carcinoma and 1.2% with adenocarcinoma.
Conclusion: The study highlights the high prevalence of precancerous cervical lesions, emphasizing the necessity of early screening. Colposcopy demonstrated higher diagnostic accuracy than Pap smear, reinforcing its role in early cervical cancer detection.
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Copyright (c) 2025 Punita Kumari, Rajeev Kumar Khetan, Pratima

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