TYPE 2 RESPIRATORY FAILURE AND LUNG RECRUITERS IN ICU SETUP: A ONE-YEAR PROSPECTIVE OBSERVATIONAL STUDY.

Rajeev  Ranjan; Utkarsh  Singh; Devendra Prasad  Singh

doi:10.51168/sjhrafrica.v5i3.1105

Authors

Rajeev Ranjan Director, Chest Hospital, Chapra, Bihar, India
Utkarsh Singh Resident, Department of Pulmonary Medicine, Bharati Vidhiyapeeth Medical College, Pune, Maharashtra, India
Devendra Prasad Singh Professor and Head, Department of Medicine, Angika Hospital and Research Centre, Patal Babu Road, Bhagalpur, Bihar, India

DOI:

https://doi.org/10.51168/sjhrafrica.v5i3.1105

Keywords:

Type 2 Respiratory Failure, Lung Recruiters, Intensive Care Unit, Chronic obstructive pulmonary disease

Abstract

Background

Respiratory failure is a critical condition commonly encountered in intensive care units (ICUs), with Type 2 Respiratory Failure (T2RF) posing significant challenges in management. This study investigates the correlation between T2RF and the effectiveness of lung recruiters in an ICU setting through a one-year observational study.

Methods

The study employed a prospective observational design and was conducted and 80 individuals meeting inclusion criteria were enrolled, while standardized data collection procedures were implemented to minimize bias. Demographic, clinical, and respiratory support data were collected and analyzed using SPSS version 21.0.

Results

Participant characteristics revealed a mean age of 65 years (± 8.2), with 65% being male. Various degrees of COPD severity were observed, with significant p-values associated with severe COPD (p<0.001) and AE-COPD (p<0.001). Upon ICU admission, participants exhibited clinical features indicative of T2RF, including mean PaO2 of 55 mmHg (± 10.2), PaCO2 of 65 mmHg (± 8.5), and pH of 7.28 (± 0.03). Statistical analysis revealed significant associations between the use of lung recruiters and improvements in oxygenation (χ²=18.23, p<0.001) and reductions in PaCO2 levels (χ²=15.87, p<0.001). Among participants who received lung recruitment strategies, 75% demonstrated improvements in oxygenation, while 65% experienced a decrease in PaCO2 levels. Complications such as ventilator-associated pneumonia occurred in 15% of cases.

Conclusion

The study underscores the importance of tailored interventions for T2RF in the ICU. Lung recruiters showed efficacy in improving respiratory parameters, with implications for optimizing patient outcomes. Vigilant monitoring for complications remains imperative.

Recommendations

Future research should focus on refining management strategies and exploring additional interventions to enhance patient care in T2RF. Additionally, investigating long-term outcomes and the impact of early intervention on mortality and morbidity rates could further guide clinical practice in ICU settings.