Clinical profile of visual disturbances in alcohol abuse: A cross-sectional observational study in a forensic medicine unit.

Authors

  • Dr. A. Kranti Kiran Assistant Professor, Department of Forensic Medicine and Toxicology, Government Medical College and General Hospital, Suryapet, Telangana, India
  • Dr. Anumula Shireesha Assistant Professor, Department of Ophthalmology, Mamatha Academy of Medical Sciences, Bachupally, Hyderabad,Telangana, India

DOI:

https://doi.org/10.51168/sjhrafrica.v6i9.2115

Keywords:

Alcohol abuse, Visual disturbances, Ocular findings, Forensic medicine

Abstract

Background:
Alcohol abuse is a major public health issue with significant neuro-ophthalmic implications. Visual disturbances are often underrecognized in chronic alcohol users, yet they may serve as important clinical markers of toxicity and chronic damage. This study aimed to evaluate the clinical spectrum and ocular findings associated with alcohol abuse in patients presenting to a forensic medicine unit.

 Methods:

This observational study included 100 individuals with a history of alcohol abuse presenting with visual complaints. Demographic details, duration and pattern of alcohol use, presenting visual symptoms, and ocular examination findings were systematically documented. Descriptive statistics were applied to analyze the data, and results were expressed as frequencies and percentages.

 Results:

The mean age of participants was 37.8 ± 9.4 years, with most cases in the 30–39 year group. Males predominated (82%). Chronic heavy alcohol use was reported in 64% of cases, with a mean duration of 8.1 ± 3.1 years. The most frequent symptoms were blurred vision (42%), diplopia (18%), photophobia (15%), and transient visual obscurations (12%). Less common complaints included reduced visual acuity (10%), color vision defects (2%), and visual hallucinations (1%). Ocular findings included conjunctival congestion (28%), nystagmus (16%), sluggish pupillary reflexes (14%), optic disc pallor (12%), hyperemia (8%), and retinal hemorrhages (5%). Seventeen percent of participants had normal ocular examinations despite subjective complaints.

 Conclusion:

Visual disturbances are common among individuals with alcohol abuse. Both reversible and irreversible ocular changes were observed, highlighting the importance of early ophthalmic evaluation in this population.

 Recommendations:

Routine ophthalmic screening should be integrated into de-addiction and rehabilitation programs. Multidisciplinary collaboration between ophthalmologists, psychiatrists, and forensic specialists is essential to prevent long-term visual morbidity.

Author Biographies

Dr. A. Kranti Kiran , Assistant Professor, Department of Forensic Medicine and Toxicology, Government Medical College and General Hospital, Suryapet, Telangana, India

obtained his MBBS from S.V.S. Medical College, Mahabubnagar, in 2009, and subsequently earned his MD in Forensic Medicine from Osmania Medical College, Hyderabad (2011–2014). He trained as a Senior Resident at Kakatiya Medical College, Warangal (2014–2015), before serving as Assistant Professor at Katuri Medical College, Guntur (2015–2016), Dr. SMCSI Medical College, Kerala (2016–2017), and ASRAM, Eluru (2017–2018). From 2018 to 2023, he worked under the Telangana Vaidya Vidhana Parishad (TVVP) as a Civil Assistant Surgeon Specialist in Forensic Medicine at AH/CHC Bhongir. Since 2023, he has been an Assistant Professor in the Department of Forensic Medicine at Government Medical College, Suryapet. His areas of academic interest include forensic toxicology, clinical forensic medicine, and medico-legal research.ORCID iD: https://orcid.org/0009-0008-6151-0246

Dr. Anumula Shireesha, Assistant Professor, Department of Ophthalmology, Mamatha Academy of Medical Sciences, Bachupally, Hyderabad,Telangana, India

is an ophthalmologist with specialized training in vitreoretinal diseases. She completed her MBBS from S.V.S. Medical College, Mahabubnagar (2006–2012), followed by a Diploma in Ophthalmology (DO) from Kamineni Institute of Medical Sciences, Narketpally, where she received a gold medal. She later obtained her DNB in Ophthalmology from Pushpagiri Vitreo Retina Institute, Hyderabad.

Her clinical expertise spans the diagnosis and management of corneal diseases, glaucoma, retinal disorders, and uveitis. She has independently performed more than 300 small-incision cataract surgeries, 60 phacoemulsification procedures, over 400 intravitreal injections, and several anterior segment procedures. She is also skilled in laser procedures, including YAG capsulotomy, YAG iridotomy, and retinal photocoagulation.

Dr. Shireesha has served as Assistant Professor of Ophthalmology at Government Medical College, Nalgonda, and has prior experience as Senior Resident at Mallareddy Institute of Medical Sciences and Junior Consultant at Pushpagiri Vitreoretinal Institute.

She has contributed to peer-reviewed publications in the Indian Journal of Ophthalmology, Indian Journal of Rheumatology, and Hepatology Communications, with research focusing on optic neuropathies, retinal diseases, and systemic associations of ocular pathology. Her professional interests include retinal diseases, neuro-ophthalmology, and medical education. ORCID iD: https://orcid.org/0009-0001-4458-5085

References

Ahuja S, Kumar PS, Kumar VP, Kattimani S, Akkilagunta S. Effect of chronic alcohol and tobacco use on retinal nerve fibre layer thickness: a case-control study. BMJ Open Ophthalmol. 2016 Nov 21;1(1):e000003. Doi: 10.1136/bmjophth-2016-000003. PMID: 29354691; PMCID: PMC5759398. https://doi.org/10.1136/bmjophth-2016-000003

Karimi S, Arabi A, Shahraki T. Alcohol and the Eye. J Ophthalmic Vis Res. 2021 Apr 29;16(2):260-270. doi: 10.18502/jovr.v16i2.9089. PMID: 34055263; PMCID: PMC8126742. https://doi.org/10.18502/jovr.v16i2.9089

Peragallo J, Biousse V, Newman NJ. Ocular manifestations of drug and alcohol abuse. Curr Opin Ophthalmol. 2013 Nov;24(6):566-73. doi: 10.1097/ICU.0b013e3283654db2. PMID: 24100364; PMCID: PMC4545665. https://doi.org/10.1097/ICU.0b013e3283654db2

Grzybowski A, et al. Toxic optic neuropathies: an updated review. Acta Ophthalmologica. 2015;93(6):453-462. https://doi.org/10.1111/aos.12515

Liberski S, Kaluzny BJ, Kocięcki J. Methanol-induced optic neuropathy: a still-present problem. Arch Toxicol. 2022;96:431-451. https://doi.org/10.1007/s00204-021-03202-0

Donnadieu-Rigole H, Daien V, Blanc D, et al. The Prevalence of Optic Neuropathy in Alcoholic Patients - A Pilot Study. Alcohol Clin Exp Res. 2014;38(7):1939-1945. https://doi.org/10.1111/acer.12468

Baj J, Forma A, Kobak J, Tyczyńska M, Dudek I, Maani A, Teresiński G, Buszewicz G, Januszewski J, Flieger J. Toxic and Nutritional Optic Neuropathies-An Updated Mini-Review. International Journal of Environmental Research and Public Health. 2022; 19(5):3092. https://doi.org/10.3390/ijerph19053092

Sajjad Ali Surhio, Shahzad Memon, Muhammad Memon, et al. Alcohol Related Toxic Optic Neuropathy Case Series. Pak J Ophthalmol. 2013;29(3):173-179

Delibes, C., Ferré, M., Rozet, M. et al. Genetic susceptibility to optic neuropathy in patients with alcohol use disorder. J Transl Med 22, 495 (2024). https://doi.org/10.1186/s12967-024-05334-0

Romano F, Tarnutzer AA, Straumann D, Ramat S, Bertolini G. Gaze-evoked nystagmus induced by alcohol intoxication. J Physiol. 2017 Mar 15;595(6):2161-2173. doi: 10.1113/JP273204. Epub 2017 Jan 17. PMID: 27981586; PMCID: PMC5350443. https://doi.org/10.1113/JP273204

Isen DR, Streitenberger JH, et al. Neuro-ophthalmic manifestations of Wernicke encephalopathy. Eye Brain. 2020;12:119-129. https://doi.org/10.2147/EB.S234078

Liberski Sławomir, et al. Methanol-induced optic neuropathy: epidemiology, molecular and clinical perspectives. Arch Toxicol. 2022;96(2):431-451. https://doi.org/10.1007/s00204-021-03202-0

Illicit drugs: Effects on the Eye (Dhingra D, Kaur S, Jagat Ram). Indian J Med Res. 2019;150(6):528-538. https://doi.org/10.4103/ijmr.IJMR_1210_17

Alcalá Torres J, Sánchez Sánchez MC, Gracia-Miguel TG, Santos Martín C, Reche Sainz JA, Ferro Osuna M. Disulfiram-Induced Optic Neuropathy: Prognostic Factors, Literature Review and Comparison with Alcohol-Tobacco Induced Optic Neuropathy. Neuro-Ophthalmology. 2025;[Epub ahead of print]. https://doi.org/10.1080/01658107.2025.2538132

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Published

2025-09-30

How to Cite

Kiran, . A. K. ., & Shireesha, D. A. . (2025). Clinical profile of visual disturbances in alcohol abuse: A cross-sectional observational study in a forensic medicine unit. Student’s Journal of Health Research Africa, 6(9), 8. https://doi.org/10.51168/sjhrafrica.v6i9.2115

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Section

Section of General Medicine Research