Evaluation of Intraocular Pressure Outcomes and Failure Risk Factors in the Collaborative Study on Bleb-Related Infection and Treatment

Marianus Deepak  Lakra; Sindhu  Kumari; Kuldeep  Chaudhary; Pinki  Patel

doi:10.51168/sjhrafrica.v5i12.1496

Authors

Marianus Deepak Lakra Associate Professor, Department of Ophthalmology, RIMS, Ranchi, Jharkhand, India
Sindhu Kumari Senior Resident, Department of Ophthalmology, RIMS, Ranchi, Jharkhand, India
Kuldeep Chaudhary Junior Resident, Department of Ophthalmology, RIMS, Ranchi, Jharkhand, India
Pinki Patel Junior Resident, Department of Ophthalmology, RIMS, Ranchi, Jharkhand, India.

DOI:

https://doi.org/10.51168/sjhrafrica.v5i12.1496

Keywords:

Glaucoma, Trabeculectomy, Intraocular Pressure, Surgical Outcomes, Complications

Abstract

Background:

Trabeculectomy remains the primary surgical intervention for glaucoma management, enhanced by adjunctive therapies like mitomycin C, despite the associated risk of complications such as bleb-related infections. The Collaborative Bleb-Related Infection Incidence and Treatment Study (CBIITS) aims to assess the incidence and risk factors for these infections.

Methods:

This prospective study included 30 patients undergoing filtering surgeries at Rajendra Institute of Medical Sciences (RIMS), Ranchi, with follow-up at six-month intervals over three years. Intraocular pressure (IOP) was measured preoperatively and postoperatively using Goldmann applanation tonometry, and surgical success was defined based on IOP thresholds from the World Glaucoma Association. Statistical analyses included Kaplan-Meier survival analysis and Cox proportional hazards models to evaluate outcomes and associated risk factors.

Results:

The study involved 30 patients with a mean age of 62.8 years and a mean follow-up of 12.3 months. Primary open-angle glaucoma was the most common diagnosis (50%). Multivariate analysis indicated that previous glaucoma surgeries significantly impacted treatment outcomes, with 76.7% of patients having no prior surgeries achieving better results. Postoperative complications were observed in 9 patients (30%), with early complications such as hyphema and choroidal detachment occurring in 6 (20%) and 10 (33.3%) cases, respectively.

Conclusion:

Surgical history and lens status are crucial for the success of trabeculectomy in glaucoma management, emphasizing the importance of monitoring postoperative complications.

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