A CROSS-SECTIONAL STUDY OF SILENT MYOCARDIAL INFARCTION AMONG TYPE 2 DIABETICS.

Abstract

Introduction:

Diabetes mellitus type 2 typically affects adults when the body doesn't produce enough insulin or grows resistant to it, leading to several micro- and macrovascular. This study used an activity treadmill test to assess the severity of silent myocardial ischemia, a significant macrovascular consequence, in a subset of asymptomatic diabetic outpatients.

Material and Methods:

The cross-sectional observational research was conducted from September 2022 to September 2023 at the Darbhanga Medical College and Hospital in Laheriasarai, Bihar, India. The study comprised 250 asymptomatic type 2 diabetes mellitus (DM) patients without clinical symptoms of coronary artery disease (CAD) and normal electrocardiograms. Patients with heart failure, angina pectoris, previous myocardial ischemia (MI), or any other chronic ailment were not eligible to participate in the trial. A silent myocardial infarction was identified by CASE/T2100 sr number GE MAC using a treadmill test (TMT) conducted following the Bruce protocol.

Results:

Silent MI was present in 12.8% of diabetic individuals with positive TMT. Diabetes for more than 10 years (p=0.001), Age (p=0.002), dyslipidemia (p=0.001), and having an HbA1c were all substantially associated with TMT favorable of more than 10% (p=0.001). It was found that TMT-positive individuals had significantly higher levels of triglycerides, LDL cholesterol, and total cholesterol than TMT-negative patients. Compared to TMT-negative patients, those who tested positive for TMT had significantly lower HDL levels.

Conclusion:

Many people experienced asymptomatic coronary artery disease or silent myocardial infarctions when they had type 2 diabetes. Silent MI was more common in diabetics who were overweight, dyslipidemic, older, and had increased HbA1C levels. When it first started, TMT might be an easy, non-invasive way to identify this.

Recommendation:

Being physically active helps you manage your diabetes because it increases your body's sensitivity to insulin, the hormone that permits your body's cells to use blood sugar for energy.