ANALYSIS OF UROPATHOGENS AND ANTIBIOTIC SENSITIVITY PATTERNS IN DIABETES MELLITUS PATIENTS AT A TERTIARY CARE HOSPITAL: AN OBSERVATIONAL STUDY.

Abstract

Background:

Diabetes Mellitus (DM), affects various systems within the body. Patients with untreated treated diabetes are at risk of developing a range of complications that contribute to increased morbidity and mortality rates. Diabetes Mellitus exerts various persistent impacts on the Urogenital system. UTIs have been widely acknowledged as a substantial concern among individuals diagnosed with DM.

Methods:

A potential observational research was conducted consisting of individuals with diabetes mellitus exhibiting positive indications of urinary tract infection. Exclusion criteria encompassed gestational diabetes, patients with compromised immune systems, and individuals presenting with congenital kidney malformations.

Results:

The study encompassed a total of 110 incidents of UTIs. Among them were a total of 35 males, and 75 females. The age group predominantly comprised between the ages of 55 and 70 years. Escherichia coli was identified as the prevailing microorganism isolated in the sample. Gram-positive organisms proved a sensitivity rate of 100% to Linezolid and Vancomycin. Gram-negative microbes demonstrated a sensitivity rate of 100% to Polymyxin B.

Conclusion:

Urogenital tract infection is a commonly observed difficulty in individuals with diabetes mellitus. The identification of the most prevalent causative organisms and their corresponding antibiotic sensitivity patterns is imperative within a tertiary care hospital setting in order to establish an enhanced antibiotic policy.

Recommendation:

It is strongly recommended that further studies be conducted with a larger sample size in order to provide additional support for the findings obtained in this study.