EVALUATION OF DIAGNOSTIC PERFORMANCE OF USG GUIDED FNAC OF THYROID SWELLINGS: A PROSPECTIVE STUDY
Keywords:USG Guided FNAC, Sensitivity, Specificity, Diagnostic Accuracy, Thyroid nodule
USG-guided FNAC is a good preoperative screening technique when compared to FNAC and USG done separately for the diagnosis of a thyroid lesion. However, there is little evidence in the literature that emphasizes the importance of USG-guided FNAC as the first step in the investigation of thyroid lesions.
Aim: Our study aims to see the sensitivity and specificity, adequacy, and diagnostic accuracy of USG-guided FNAC taking histopathology as a gold standard.
This Hospital-based prospective observational study was carried out on patients who attended the OPD and/or IPD and underwent surgery in the Department of Otorhinolaryngology.
The sensitivity, specificity, and diagnostic accuracy of ultrasound-guided FNAC for thyroid lesions were 58.82%, 98.18%, and 88.89% respectively taking Bethesda categories 1 to 3 as benign and categories 4 to 6 as malignant. The positive likelihood ratio and negative likelihood ratio are 32.32 and 0.42 respectively. Positive predictive value and negative predictive value were 90.91% and 88.52%. The diagnostic accuracy of USG-guided FNAC for thyroid lesions in the present study is 88.89% and adequacy is 93.05%.
Further study of a larger number of cases is desirable. US-FNAC is an expensive procedure as compared to palpable FNAC.
We recommend the application of USG guide FNAC as the first step in the investigation of thyroid lesions along with a detailed interdepartmental correlation to make the diagnosis before surgery.
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Copyright (c) 2023 Kumari Jyoti Mani, Neha Kumari, Arushi Kumar, Satyendra Sharma, Nageswar Sahu
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