Factors influencing adherence to iron and folic acid among primigravidae seeking antenatal care in Mbarara district, Southwestern Uganda. A cross-sectional study.

Authors

  • Hector Ankunda Department of Internal Medicine, Mbarara Doctors’ plaza hospital, P.O. Box 420978, Mbarara, Uganda.
  • Shillah Ashaba Department of Internal Medicine, Mbarara Doctors’ plaza hospital, P.O. Box 420978, Mbarara, Uganda.
  • Victor Prosper Department of Internal Medicine, Mbarara Doctors’ plaza hospital, P.O. Box 420978, Mbarara, Uganda.
  • Jordan Amanyire Department of Public Health, Faculty of Health Sciences, Bishop Stuart University, P.O. Box 09, Mbarara, Uganda.
  • Daniel Matovu Department of Public Health, Faculty of Health Sciences, Bishop Stuart University, P.O. Box 09, Mbarara, Uganda

DOI:

https://doi.org/10.51168/sjhrafrica.v6i9.2025

Keywords:

Primigravidas, Adherence, Iron and folic acid supplements, Mbarara district

Abstract

Background

This study aimed at determining the factors influencing adherence to iron and folic acid among primigravidae seeking antenatal care in Mbarara district, Southwestern Uganda.

 Methods

This was a cross-sectional study done within Mbarara district among primigravidae seeking antenatal care.  Proportionate probability sampling and simple random sampling techniques were used to select 172 primigravidae seeking antenatal care in Mbarara district. Interviews were done using a researcher-administered questionnaire with a quantitative approach. Data was entered in Excel, cleaned, and exported to Stata version 17 for analysis. Logistic regression was used to determine factors associated with adherence to iron and folic acid supplements among primigravidae.

 Results

The proportion of primigravidae attending antenatal care in Mbarara district whose adherence to iron and folic acid supplements was defined as taking at least 80% of the prescribed iron and folic acid supplements was 64.53% (95% CI 0.52 – 0.63).

Adherence was associated with age bracket 20-29 years (AOR=4.57, 95%CI: 2.05-11.13), having a reminder to take iron and folic acid supplements (AOR=2.81, 95% CI: 1.33-5.92) and being counselled on the importance of taking iron and folic acid supplements (AOR=4.45, 95% CI: 2.07-9.31).

 Conclusions

The level of adherence to iron and folic acid supplements among primigravidae attending ANC in Mbarara district is relatively high (6 in every 10 primigravidae). Primigravidas who are less than 30 years old, with a reminder to take iron and folic acid supplements and counselling from health workers about the importance of iron and folic acid supplements during pregnancy, are more likely to adhere to iron and folic acid supplements.

 Recommendation

Intensive and daily counselling about the importance of iron and folic acid supplements during pregnancy should be done by antenatal care providers, especially to primigravidae who are 30 years of age or older.

References

BA, D. M., SSENTONGO, P., KJERULFF, K. H., NA, M., LIU, G., GAO, X. & DU, P. 2019. Adherence to iron supplementation in 22 sub-Saharan African countries and associated factors among pregnant women: a large population-based study. Current developments in nutrition, 3, nzz120. https://doi.org/10.1093/cdn/nzz120

BOTI, N., BEKELE, T., GODANA, W., GETAHUN, E., GEBREMESKEL, F., TSEGAYE, B. & OUMER, B. 2018. Adherence to Iron-Folate supplementation and associated factors among Pastoralists' pregnant women in Burji districts, Segen area People's zone, southern Ethiopia: community-based cross-sectional study. International journal of reproductive medicine, 2018. https://doi.org/10.1155/2018/2365362

GEBRE, A., MULUGETA, A. & ETANA, B. 2015b. Assessment of factors associated with adherence to iron-folic acid supplementation among urban and rural pregnant women in North Western Zone of Tigray, Ethiopia: a comparative Study. International Journal of Nutrition and Food Sciences, 4, 161. https://doi.org/10.11648/j.ijnfs.20150402.16

GEBREMARIAM, A. D., TIRUNEH, S. A., ABATE, B. A., ENGIDAW, M. T. & ASNAKEW, D. T. 2019. Adherence to iron with folic acid supplementation and its associated factors among pregnant women attending antenatal care follow-up at Debre Tabor General Hospital, Ethiopia, 2017. PloS one, 14, e0210086. https://doi.org/10.1371/journal.pone.0210086

GEBREMICHAEL, T. G. & WELESAMUEL, T. G. 2020. Adherence to iron-folic acid supplement and associated factors among antenatal care attending pregnant mothers in governmental health institutions of Adwa town, Tigray, Ethiopia: Cross-sectional study. PLoS One, 15, e0227090. https://doi.org/10.1371/journal.pone.0227090

KIWANUKA, T. S., ONONGE, S., KIONDO, P. & NAMUSOKE, F. 2017. Adherence to iron supplements among women receiving antenatal care at Mulago National Referral Hospital, Uganda: a cross-sectional study. BMC research notes, 10, 1-6. https://doi.org/10.1186/s13104-017-2834-z

LYOBA, W. B., MWAKATOGA, J. D., FESTO, C., MREMA, J. & ELISARIA, E. 2020. Adherence to iron-folic acid supplementation and associated factors among pregnant women in Kasulu communities in north-western Tanzania. International Journal of Reproductive Medicine, 2020. https://doi.org/10.1155/2020/3127245

MAMO, T. T., ASHENAFI, E., GUBE, A. A. & BEKELE, T. 2021. Adherence to prenatal iron-folic acid supplementation and associated factors among pregnant women attending antenatal care services in Dilla town, South Ethiopia. Medicine Access @ Point of Care, 5, 23992026211008805. https://doi.org/10.1177/23992026211008805

MARTIN, S. L., OMOTAYO, M. O., CHAPLEAU, G. M., STOLTZFUS, R. J., BIRHANU, Z., ORTOLANO, S. E., PELTO, G. H. & DICKIN, K. L. 2017. Adherence partners are an acceptable behaviour change strategy to support calcium and iron-folic acid supplementation among pregnant women in Ethiopia and Kenya. Matern Child Nutr, 13. https://doi.org/10.1111/mcn.12331

MBHENYANE, X. & CHERANE, M. 2017. Compliance with the consumption of iron and folate supplements by pregnant women in Mafikeng local municipality, North West Province, South Africa. African health sciences, 17, 657-670. https://doi.org/10.4314/ahs.v17i3.8

MITHRA, P., UNNIKRISHNAN, B., REKHA, T., NITHIN, K., MOHAN, K., KULKARNI, V., HOLLA, R. & AGARWAL, D. 2014. Compliance with iron-folic acid (IFA) therapy among pregnant women in an urban area of South India. African health sciences, 14, 255-260. https://doi.org/10.4314/ahs.v14i1.39

NASIR, B. B., FENTIE, A. M. & ADISU, M. K. 2020. Adherence to iron and folic acid supplementation and prevalence of anemia among pregnant women attending antenatal care clinic at Tikur Anbessa Specialized Hospital, Ethiopia. Plos one, 15, e0232625. https://doi.org/10.1371/journal.pone.0232625

NIMWESIGA, C., MUREZI, M. & TAREMWA, I. M. 2021. Adherence to Iron and Folic Acid Supplementation and Its Associated Factors among Pregnant Women Attending Antenatal Care at Bwindi Community Hospital, Western Uganda. Int J Reprod Med, 2021, 6632463. https://doi.org/10.1155/2021/6632463

NISAR, Y. B., DIBLEY, M. J. & MIR, A. M. 2014. Factors associated with non-use of antenatal iron and folic acid supplements among Pakistani women: a cross-sectional household survey. BMC Pregnancy and Childbirth, 14, 305. https://doi.org/10.1186/1471-2393-14-305

ORGANIZATION, W. H. 2012. The global prevalence of anaemia in 2010, World Health Organization.

ORGANIZATION, W. H. 2015. World Malaria Report 2014, World Health Organization.

SECK, B. C. & JACKSON, R. T. 2008. Determinants of compliance with iron supplementation among pregnant women in Senegal. Public health nutrition, 11, 596-605. https://doi.org/10.1017/S1368980007000924

SENDEKU, F. W., AZEZE, G. G. & FENTA, S. L. 2020. Adherence to iron-folic acid supplementation among pregnant women in Ethiopia: a systematic review and meta-analysis. BMC pregnancy and childbirth, 20, 1-9. https://doi.org/10.1186/s12884-020-2835-0

PRADHAN, BEHERA & RAMANI. 2024. FACTORS AFFECTING ADHERENCE TO IRON AND FOLIC ACID SUPPLEMENTATION DURING ANTENATAL CARE AT ANGANWADI CENTRE FOR ANTENATAL CHECK UPS, INDIA.

BALCHA, ETEFFA & TESFU. 2023. Maternal Knowledge of Anemia and Adherence to Its Prevention Strategies: A Health Facility-Based Cross-Sectional Study Design. https://doi.org/10.1177/00469580231167731

OIYE., JUMA & KONYOLE. 2020. The Influence of Antenatal Oral Iron and Folic Acid Side Effects on Supplementation Duration in Low-Resource Rural Kenya: A Cross-Sectional Study https://doi.org/10.1155/2020/9621831

SARAGIH., DIMOG & LIN. 2022. Adherence to Iron and Folic Acid Supplementation (IFAS) intake among pregnant women: A systematic review meta-analysis https://doi.org/10.1016/j.midw.2021.103185

Downloads

Published

2025-09-01

How to Cite

Ankunda, H., Ashaba , S., Prosper , V., Amanyire, J. ., & Matovu, . D. (2025). Factors influencing adherence to iron and folic acid among primigravidae seeking antenatal care in Mbarara district, Southwestern Uganda. A cross-sectional study. Student’s Journal of Health Research Africa, 6(9), 12. https://doi.org/10.51168/sjhrafrica.v6i9.2025

Issue

Section

Section of Obstetrics and Gynecology Research