Seroprevalence of TTI among blood donors at the blood center, Lalitpur: A 4-year study
Keywords:
Prevalence, Transfusion-transmitted Infections, Blood Donor, Blood Centre, HIVAbstract
Background- Millions of lives are saved by timely, safe, and enough transfusions; yet inappropriate transfusions raise the risk of transfusion-transmitted infections (TTIs) and cause numerous potentially fatal consequences. All infections that can spread from person to person by parenterally administering blood or blood products are known as TTIs.
Objectives- At a blood center at Autonomous State Medical College (ASMC), Lalitpur, Uttar Pradesh, the study sought to ascertain the TTIs prevalence in both replacement and voluntary donors.
Materials and Methods- Data that were collected on donors of blood collected at a blood center between 2021 and 2024 was the subject of retrospective descriptive research. Data that were extracted from the database included age, sex, and donation type. The outcomes were total TTI, syphilis seropositivity, HIV, HBV, and HCV.
Results- Male donors made up 95.6% of all participants, while female donors made up just 4.4%, according to the researchers. In terms of blood donor types, family donors accounted for 81% of the total, while donors who donated voluntarily made up 19%. The data was not found to be significant among TTIs in various years with a p-value of 0.24.
Conclusion-The study concludes that the prevalence of transfusion-transmitted infections is medium and has been declining over time. The most common infection is hepatitis B (HBsAg), which is followed by syphilis, HIV, and HCV.
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Copyright (c) 2025 Priya Jain, Dharmendra Kumar, Amrita Tripathi, Piyush Jain, Shruti Singh
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