CLINICAL CHARACTERISTICS AND ENDOSCOPIC FINDINGS OF SYMPTOMATIC DYSPEPSIA PATIENTS IN RURAL AND URBAN AREAS: A RETROSPECTIVE COMPARATIVE STUDY.

Authors

  • Kaibalya Ranjan Dash Assistant Professor, Department of Gastroenterology, SCB Medical College & Hospital Cuttack, Odisha, India
  • Amulya Ranjan Dash  MD, Department of Anesthesiology, Carcinova Cancer Hospital, Cuttack, Odisha, India

DOI:

https://doi.org/10.51168/sjhrafrica.v5i12.1512

Keywords:

Dyspepsia, Helicobacter Pylori, Endoscopy, Rural And Urban Populations, Gastrointestinal Disorders

Abstract

Background

Dyspepsia is a common gastrointestinal disorder affecting a substantial portion of the global population, characterized by various symptoms such as epigastric pain and early satiety. Understanding the differences in dyspeptic presentations among diverse populations can inform more effective diagnostic and treatment strategies. This study seeks to contrast the clinical characteristics and endoscopic findings of dyspeptic patients from rural and urban areas.

Methods

This retrospective comparative study was conducted at SCB Medical College & Hospital in Cuttack over one year, involving 100 patients diagnosed with dyspepsia. Participants were selected using non-probability consecutive sampling, with inclusion criteria focused on individuals aged 16 to 75 years presenting with relevant gastrointestinal symptoms. Endoscopic evaluations were performed to assess the underlying conditions.

Results

The study revealed that the majority of patients were aged 31-40 years (25%), with a slight female predominance (55%). The rapid urease test indicated a 60% positive rate for Helicobacter pylori infection among participants. Notable endoscopic findings included erosive antral gastritis observed in 30 rural patients and 35 urban patients, highlighting the differences in gastrointestinal conditions between populations.

Conclusion

The findings underscore the need for tailored healthcare interventions based on demographic factors, as urban patients exhibited a higher prevalence of certain dyspeptic symptoms. This study emphasizes the importance of understanding the clinical and endoscopic variations of dyspepsia to enhance patient care.

Recommendations

Initial endoscopy for new-onset dyspepsia is recommended in patients 50 years of age or older or those with alarm features.

References

Mahadeva, S., & Goh, K. L. (2006). Epidemiology of functional dyspepsia: a global perspective. World journal of gastroenterology: WJG, 12(17), 2661. https://doi.org/10.3748/wjg.v12.i17.2661

Bytzer, P., & Talley, N. J. (2001). Dyspepsia. Annals of Internal Medicine, 134(9_Part_2), 815-822. https://doi.org/10.7326/0003-4819-134-9_Part_2-200105011-00004

De Bortoli, N., Tolone, S., Frazzoni, M., Martinucci, I., Sgherri, G., Albano, E., ... & Marchi, S. (2018). Gastroesophageal reflux disease, functional dyspepsia, and irritable bowel syndrome: common overlapping gastrointestinal disorders. Annals of Gastroenterology, 31(6), 639. https://doi.org/10.20524/aog.2018.0314

Quigley, E. M., & Lacy, B. E. (2013). Overlap of functional dyspepsia and GERD-diagnostic and treatment implications. Nature Reviews Gastroenterology & hepatology, 10(3), 175-186. https://doi.org/10.1038/nrgastro.2012.253

Wang, Z., Liu, T., Cao, D., Luo, H., Yang, Z., Kang, X., & Pan, Y. (2024). The associations between functional dyspepsia and potential risk factors: A comprehensive Mendelian randomization study. Plos one, 19(5), e0302809. https://doi.org/10.1371/journal.pone.0302809

Oustamanolakis, P., & Tack, J. (2012). Dyspepsia: organic versus functional. Journal of Clinical Gastroenterology, 46(3), 175-190. https://doi.org/10.1097/MCG.0b013e318241b335

Talley, N. J., Silverstein, M. D., Agreus, L., Nyren, O., Sonnenberg, A., & Holtmann, G. (1998). AGA technical review: evaluation of dyspepsia. Gastroenterology, 114(3), 582-595. https://doi.org/10.1016/S0016-5085(98)70542-6

Graham, D. Y., & Rugge, M. (2010). Clinical practice: diagnosis and evaluation of dyspepsia. Journal of Clinical Gastroenterology, 44(3), 167-172. https://doi.org/10.1097/MCG.0b013e3181c64c69

Health and Public Policy Committee. (1985). Endoscopy in the evaluation of dyspepsia. Annals of Internal Medicine, 102(2), 266-269. https://doi.org/10.7326/0003-4819-102-2-266

Li, M., Lu, B., Chu, L., Zhou, H., & Chen, M. Y. (2014). Prevalence and characteristics of dyspepsia among college students in Zhejiang Province. World Journal of Gastroenterology: WJG, 20(13), 3649. https://doi.org/10.3748/wjg.v20.i13.3649

Mahadeva, S., Yadav, H., Rampal, S., Everett, S. M., & GOH, K. L. (2010). Ethnic variation, epidemiological factors and quality of life impairment associated with dyspepsia in urban Malaysia. Alimentary pharmacology & therapeutics, 31(10), 1141-1151. https://doi.org/10.1111/j.1365-2036.2010.04270.x

Schmidhuber, J., & Shetty, P. (2005). The nutrition transition to 2030. Why developing countries are likely to bear the major burden? Acta agriculturae scand section c, 2(3-4), 150-166. https://doi.org/10.1080/16507540500534812

Papatheodoridis, G. V., & Karamanolis, D. G. (2005). Prevalence and impact of upper and lower gastrointestinal symptoms in the Greek urban general population. Scandinavian journal of gastroenterology, 40(4), 412-421. https://doi.org/10.1080/00365520510012271

Ghoshal, U. C., & Singh, R. (2017). Frequency and risk factors of functional gastro‐intestinal disorders in a rural Indian population. Journal of gastroenterology and hepatology, 32(2), 378-387. https://doi.org/10.1111/jgh.13465

Popkin, B. M. (2006). Global nutrition dynamics: the world is shifting rapidly toward a diet linked with noncommunicable diseases. The American journal of clinical nutrition, 84(2), 289-298. https://doi.org/10.1093/ajcn/84.2.289

Fleischhacker, S. E., Evenson, K. R., Rodriguez, D. A., & Ammerman, A. S. (2011). A systematic review of fast food access studies. Obesity reviews, 12(5), e460-e471. https://doi.org/10.1111/j.1467-789X.2010.00715.x

Sallis, J. F., & Glanz, K. (2006). The role of built environments in physical activity, eating, and obesity in childhood. The future of children, 89-108. https://doi.org/10.1353/foc.2006.0009

Siddique, I., Al-Qabandi, A., Al-Ali, J., Alazmi, W., Memon, A., Mustafa, A. S., & Junaid, T. A. (2014). Association between Helicobacter pylori genotypes and severity of chronic gastritis, peptic ulcer disease and gastric mucosal interleukin-8 levels: Evidence from a study in the Middle East. Gut pathogens, 6, 1-10. https://doi.org/10.1186/s13099-014-0041-1

Koloski, N. A., Talley, N. J., & Boyce, P. M. (2002). Epidemiology and health care seeking in the functional GI disorders: a population-based study. Official journal of the American College of Gastroenterology| ACG, 97(9), 2290-2299. https://doi.org/10.1111/j.1572-0241.2002.05783.x

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Published

2024-12-31

How to Cite

Dash, K. R. ., & Dash, A. R. . (2024). CLINICAL CHARACTERISTICS AND ENDOSCOPIC FINDINGS OF SYMPTOMATIC DYSPEPSIA PATIENTS IN RURAL AND URBAN AREAS: A RETROSPECTIVE COMPARATIVE STUDY. Student’s Journal of Health Research Africa, 5(12), 6. https://doi.org/10.51168/sjhrafrica.v5i12.1512

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Section

Section of General Medicine Research