Correlation of Clinical Severity and Laboratory Parameters with Different Serotypes in Dengue Virus

Authors

  • Sunil Kumar Assistant Professor, Department of Microbiology, ANMMC, Gaya, Bihar, India
  • Ravi Kumar Assistant Professor, Department of Microbiology, ANMMC, Gaya, Bihar, India.
  • Shashi Kishore Assistant Professor, Department of Microbiology, ANMMC, Gaya, Bihar, India
  • Sanjay Nag HOD, Department of Microbiology, ANMMC, Gaya, Bihar, India.

DOI:

https://doi.org/10.51168/sjhrafrica.v5i6.1277

Keywords:

Dengue, Liver Enzymes, Serotype

Abstract

Background: Dengue is a common illness in specific areas, also the symptom of dengue coincides with many other illnesses. Thus, diagnosis of the disease becomes difficult, further adds to the existing complexity. This study is conducted to identify the diagnostic and prognostic marker of dengue, which indicates the severity of the disease.

Method: This study was conducted prospectively. The106 patients who visited the hospital with positive primary dengue infection test and those with positive secondary dengue infection test were included. The demography, clinical symptoms, laboratory investigation, comorbid conditions, the treatment given, and the outcome obtained were recorded. Serotypes were determined using RTPCR.

Results: DEN-V-3 was the common serotype observed in this study. There were coinfections reported in serotypes were more than 2. Patients with severe dengue had liver enzymes AST above 134U/L, ALT above 88 U/L, and ferritin above 3670ng/ ml. Mucoskeletal symptoms were most common after that gastrointestinal symptoms, respiratory symptoms and cutaneous were not reported significantly

Conclusion: DEN-V-3 was the common serotype reported for this cohort. Ferritin and liver enzymes can be used as prognostic marker of severity of dengue.

Recommendation: Liver enzymes and ferritin should be monitored regularly to determine the prognosis.

Published

2024-06-30

How to Cite

Sunil Kumar, Ravi Kumar, Shashi Kishore, & Sanjay Nag. (2024). Correlation of Clinical Severity and Laboratory Parameters with Different Serotypes in Dengue Virus. Student’s Journal of Health Research Africa, 5(6). https://doi.org/10.51168/sjhrafrica.v5i6.1277

Issue

Section

Section of Microbiology Research