Research Comparing Peritumoral Injection of Methylene Blue Dye with Peri Areolar Injection as a Single Approach for the Identification of Sentinel Lymph Nodes in Individuals with Clinically Non-Palpable Breast Cancer

Authors

  • Kaushalendra Kumar  Senior Resident, Department of General Surgery, I. G. I. M. S., Patna, Bihar, India
  • Sujit Kumar Sah  Senior Resident, Department of General Surgery, I. G. I. M. S., Patna, Bihar, India
  • Ankit Raj Senior Resident, Department of General Surgery, I. G. I. M. S., Patna, Bihar, India
  • Pawan Kumar Jha Professor & H.O.D., Department of General Surgery, I. G. I. M. S., Patna, Bihar, India

Keywords:

Peri areolar, sentinel lymph node, peritumoral injection, methylene blue dye

Abstract

Background: Selecting the optimal place for injecting the blue dye in breast cancer is one of the most hotly contested questions in the SLN detection procedure. The injection techniques for peri areolar and peritumoral MBD have been compared in several studies. None, nevertheless, have evaluated the two in conjunction as opposed to using just one method.

Objective: In contrast to combining peri areolar and peritumoral injection techniques, the study's objective is to assess the SLN's detection rate utilizing peri areolar injection technique. This type of research will be helpful in standardizing the SLN approach in a tertiary care setting using MBD, hence avoiding axillary dissection in cases of early breast cancer.

Methods: This is a prospective comparative investigation with a sample size of 60 patients. Female individuals with early-stage breast cancer who were medically non-palpable and had histopathological confirmation were included. Essential workup was done which included basic routinely done OT investigations which are blood investigations, electrocardiogram and chest Xray. All patients provided informed written permission, after which they were split into two groups at random for injection of methylene blue dye for sentinel lymph node biopsy.

Results: Comparison of age in the study population is statistically significant (p value = 0.8245) and comparison of tumor site among population, upper quadrant is maximum in group A (46.67%) and B (60%) both. Comparison of histological types of carcinoma breast is not statistically significant.

Conclusion: The study found that using a 1% Methylene Blue Dye (MBD) solution is sufficient for Sentinel Node Biopsy (SNB) in breast cancer cases, even in clinical settings with limited access. .

Published

2024-03-31

How to Cite

Kumar, K. ., Sah, S. K., Raj, A. ., & Jha, P. K. . (2024). Research Comparing Peritumoral Injection of Methylene Blue Dye with Peri Areolar Injection as a Single Approach for the Identification of Sentinel Lymph Nodes in Individuals with Clinically Non-Palpable Breast Cancer. Student’s Journal of Health Research Africa, 5(3). Retrieved from https://sjhresearchafrica.org/index.php/public-html/article/view/1093

Issue

Section

Section of Anesthesia and Surgery Research