Study of highly sensitive C-reactive protein in type 2 diabetes mellitus and prediction of cardiovascular risk with glycemic status

Authors

  • Rakesh Kumar Professor, Department of Pediatrics, NMCH, Patna Bihar-800002 Contact no- 8797264868
  • Priyanka Prasad Assistant Professor, Dept. of Biochemistry
  • Rajiv Ranjan Sinha Professor & HOD, Biochemistry ; NMCH.

Keywords:

Glycaemic Control, Diabetes, Hs-CRP, Cardiovascular Risk, Hbalc, Insulin Resistance

Abstract

Background: hs-CRP measurement may be useful for assessment of the risk of complication in diabetes patients. So, the present study is conducted to measure plasma hs- CRP level in T2DM and to determine adequate glycaemic control reduces hs-CRP level.

Aims and objectives: The objectives of this study were to correlate HbA1c and hs-CRP in T2DM and predict cardiovascular risk with glycaemic status.

Methods: Authors took 50 diabetic patients. The investigation includes FBS, PPBS, hs- CRP and HbA1c. hs-CRP is measured by immunoturbidimetry method. The reports were collected and compared with normal reference range.

Results: The correlation between hs-CRP levels and HbA1c level after six months show a significant relationship where mean HbA1c values on day 1 and after 6 months were 8.088±1.219 and 7.518±0.693 respectively. The hs-CRP values were 2.508±1.050 on day 1 and 2.15±0.927 after 6 months proving that better glycaemic controls decrease hs-CRP thereby decreasing cardiovascular risk.

 

Conclusions: hs-CRP values are directly related to HbA1c and better glycaemic control reduces risk of CVD.

Published

2024-03-31

How to Cite

Kumar, . R. ., Prasad, P. ., & Sinha, R. R. . (2024). Study of highly sensitive C-reactive protein in type 2 diabetes mellitus and prediction of cardiovascular risk with glycemic status. Student’s Journal of Health Research Africa, 5(3). Retrieved from https://sjhresearchafrica.org/index.php/public-html/article/view/1090

Issue

Section

Section of Non-communicable Diseases Research