A CROSS-SECTIONAL STUDY ON ENHANCING SURGICAL SAFETY: INVESTIGATING ANTIBIOTIC USE IN ENDOUROLOGICAL SURGERY PERIOPERATIVE CARE.

Pratyush  Ranjan; Siddharth Jai  Singh; Tabish  Rayee

doi:10.51168/sjhrafrica.v5i3.1070

Authors

Pratyush Ranjan Consultant Urologist, Department of Urology, Lifecare Hospital, Dahiyawan, Chapra, Bihar, India
Siddharth Jai Singh Consultant Urologist, Department of Urology, Healing Touch, Bhagalpur, Bihar, India
Tabish Rayee Consultant Urologist, Department of Urology, Rayee Nursing Home, Patna, Bihar, India

DOI:

https://doi.org/10.51168/sjhrafrica.v5i3.1070

Keywords:

Endourological Surgery, Antibiotic Prophylaxis, Urinary Tract Infection, Antimicrobial Resistance

Abstract

Background

Surgical safety is paramount in healthcare, particularly in endourological surgery, where perioperative antibiotic use plays a crucial role in preventing postoperative infections. The objective of the study was to assess the patterns and efficacy of perioperative antibiotic usage in endourological surgery. This was achieved through a cross-sectional analysis aimed at elucidating current practices and evaluating their impact on patient outcomes and antimicrobial stewardship.

Methods

A cross-sectional study was conducted involving 150 participants undergoing elective endourological procedures. Data on demographics, preoperative antibiotic usage, perioperative antibiotic administration, infectious complications, and surgical details were collected using standardized protocols. Statistical analyses were employed to examine associations and outcomes with a significance level set at p< 0.05.

Results

Involving 150 participants with diverse demographics, the study found a mean age of 57 years (range: 35-75 years), with 65% male and 35% female representation. Preoperatively, 45% of participants exhibited positive urine cultures for urinary tract infections (UTIs), despite 60% receiving antibiotic prophylaxis. Intraoperatively, 25% received additional antibiotics, primarily due to prolonged surgical duration and complications. Postoperatively, 40% required prolonged antibiotic therapy, with 20% experiencing UTIs. Significant correlations were found between preoperative antibiotic use and postoperative UTIs (p < 0.05) and prolonged surgery duration and infectious complications (p < 0.01). No significant differences in UTI rates were observed across different procedures.

Conclusion

Despite prophylactic antibiotic administration, UTIs remained prevalent, emphasizing the need for optimized antibiotic regimens. Prolonged surgery duration emerged as a risk factor for infections, underscoring the importance of surgical efficiency. Tailored approaches to antibiotic prophylaxis and antimicrobial stewardship programs are warranted to mitigate the risk of antimicrobial resistance and improve patient outcomes.

Recommendations

The development of evidence-based guidelines, implementation of antimicrobial stewardship programs, enhancement of surveillance systems, and ongoing education for healthcare providers are proposed to optimize perioperative antibiotic usage in endourological surgery.