EVALUATION OF SERUM TROPONIN I LEVEL IN SEVERE ACUTE RESPIRATORY SYNDROME CORONA VIRUS 2 (SARS COV2) INFECTED PATIENTS ADMITTED IN CORONA VIRUS (COVID) WARD AND INTENSIVE CARE UNIT IN SILCHAR MEDICAL COLLEGE AND HOSPITAL, ASSAM: A RETROSPECTIVE STUDY.

Abstract

Background: 

The pandemic of COVID-19 led to the mortality of a large number of people worldwide. In several studies carried out in different parts of the world, it was seen that cardiac troponin I is a prognosticating biochemical marker of SARS-CoV2-infected patients. This present study aimed to evaluate the serum troponin I level in severe acute respiratory syndrome coronavirus 2 infected patients admitted to covid ward and COVID ICU and to find out any relationship between cardiac Troponin I and disease prognosis. This will aid in early diagnosis.

 Methodology:

102 patients participated in this study. Among the 102 patients of SARS COV 2 infection, 49 patients were taken from the Covid ward suffering from mild or moderate form of the disease. The remaining 53 patients were taken from the ICU who were critically ill. Serum cardiac Troponin I value was collected from the Laboratory Information System of the hospital and all the data was analyzed statistically.

 Results: 

Cardiac Troponin I level is higher in covid positive critically ill patients admitted to ICU with COVID-19. The median (IQR) value of serum cardiac Troponin I is significantly higher (0.0190 ng/ml) in COVID-19 ICU patients than in the COVID patients of the General ward (0.0120 ng/ml). The difference was found to be significant with a p-value of 0.00. A p-value of <0.05 was considered statistically significant.

 Conclusion: 

Serum Troponin I can be used as a prognosticating marker in COVID-19 infection and a marker of ICU admission in COVID-19-positive patients.

 Recommendation: 

More studies will be required with a large number of study samples to establish the findings of the present study.