A STUDY ON THE EVALUATION OF BRAIN BY MAGNETIC RESONANCE IMAGING IN PAEDIATRIC PATIENTS WITH DEVELOPMALESTAL DELAY

Nivedita  Jha; Deepak  Kumar; Anand Kumar  Gupta; Amit  Kumar; Sanjay Kumar  Suman

doi:10.51168/sjhrafrica.v5i9.1376

Authors

Nivedita Jha Junior Resident, Department of Radio-diagnosis, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
Deepak Kumar Additional Professor, Department of Radio-diagnosis, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
Anand Kumar Gupta Additional Professor, Department of Paediatrics, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India
Amit Kumar Additional Professor, Department of Radio-diagnosis, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India4
Sanjay Kumar Suman Professor, Department of Radio-diagnosis, Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India

DOI:

https://doi.org/10.51168/sjhrafrica.v5i9.1376

Keywords:

Developmental delay, Paediatric patients, MRI Brain, HIE, Corpus Callosum

Abstract

Introduction: One major neuromorbidity that affects children and may have long-term effects on quality of life is developmental delay (DD). MRI has become a key tool in evaluating these patients. This study aimed to assess DD in Indian children to facilitate early diagnosis, aiding physicians in providing targeted treatment and parental counseling.

Methods: This hospital-based prospective observational study included 100 pediatric patients referred for MRI brain evaluation due to developmental delay between January 2021 and July 2022. MRI scans were performed using 1.5 Tesla superconducting MRI machines (GE Optima MR360, Optima MR450W GEM, and SIGNA Artist) with appropriate sequences and planes, using sedation when necessary under anesthetist guidance. The brain's anatomical structures were assessed systematically for normalcy and maldevelopmental, and the findings were categorized into different etiological groups.

Results: Normal MRI finding were seen in 13% of the participants with DD. Abnormal findings were seen in 87% of the cases in which the most commonly affected anatomical areas were white matter, ventricles and the corpus callosum. Neurovascular etiology accounted for 53% of cases, followed by 14% for congenital and developmental etiology, 13% for metabolic and neurodegenerative etiology, 4% for nonspecific findings, 2% for neoplastic lesions, and 1% for multifactorial etiology.

Conclusion: Clinical examination and analysis are the first steps in diagnosing developmental delay, but brain imaging should be done to rule out any causes and provide appropriate management. Due to its great soft tissue resolution, MRI brain is the best imaging modality.

Recommendations: MRI should be standard in assessing pediatric developmental delay due to its high sensitivity and specificity in detecting abnormalities. It aids early diagnosis and guides targeted treatment. Larger studies are needed to refine diagnostic criteria and better understand MRI's role.